Solution Overview

Our solution for Pre-Clinical and Toxicology Data Sciences includes:

  • Effective lab data management using ELNs and/or LIMS to organize and link all results for a program or compound, ensuring that physical stock matches expectations.
  • In-silico prediction of ADME, PK, PD, and toxicity using machine learning and AI, incorporating public models and in-house data.
  • Flexible enterprise architecture that enables connections between pre-clinical systems and upstream discovery systems for the purposes of refining discovery and screening processes.
  • PK/PD modeling and mathematical expertise to enable accurate dose estimation for clinical trials.

Solution Benefits

Partnering with bPrescient benefits your R&D program in a variety of ways:

  • Gaining a comprehensive picture of pre-clinical assay results for lead molecules and programs leads to faster and more accurate decision-making.
  • Predictive models using in-house and public data enable more confident prioritization of lab assays and validation.
  • Connections of pre-clinical data with discovery and clinical groups drives more efficient operations across the organization, reducing duplication of effort and delivering cost savings.
  • Adding QSP capacity to your team as driven by pipeline milestones.

Relevant Expertise

This service draws on our expertise in the following areas:

  • Strategy & Roadmap Development
  • Scientific Informatics: Software Design and Implementation
  • Laboratory Data Systems Design, Integration & Optimization
  • AI & Machine Learning: Generating Novel Insights
  • Computational Sciences for Biology & Chemistry Research
  • Data Engineering, MLOps, and CloudOps

Learn more about our expertise

Example Tools and Data Sources

We use a variety of tools and data sources to meet specific client needs, including the following:

Data Sources

  • DrugBank
  • ChEMBL
  • BindingDB
  • IUPHAR/BPS

Tools

  • PK-Sim & MoBi
  • NONMEM
  • SwissADME
  • Dotmatics ChemELN
  • Benchling
  • GraphPad Prism

Let’s talk

Tell us about your toughest R&D challenge and let’s discuss how bPrescient can solve it.

+1 781 312 9317
info@bprescient.com